Optofluidic Microscopy-based Cell Sorting (OMiCS) is an emerging technology that combines molecular imaging with optical trapping technology and cell sorting capabilities. It is based on fluorescent molecular biomarkers (e.g., antibodies or fluorophores) and secondary cellular characteristics, such as the cell shape or other alterations of cellular morphology.
OMiCS unifies the advantages of fully automated cell separation (FACS comes closest in its properties) and conventional light microscopy. OMiCS has the following clear advantages over FACS for the given application: